He said the family was at the young girl's bedside and they are "trying to keep her here with us".
This weekend's violence spree started Friday evening, lasting through the early hours of Monday morning; with most of the violent attacks taking place Saturday.
"My grandbaby did not deserve this", Patsy Holmes, grandmother of the critically wounded 11-year-old, told ABC Chicago station WLS-TV.
The 11-year-old was transported to Comer Children's Hospital.
Prayers go out to the memory of Takiya Holmes and her family, and also to Kanari Gentry-Bowers and her family. The area has several security cameras, and Alderman Ray Lopez believes one of them captured the intended targets of the shooting.
The 12-year-old girl sustained a gunshot wound to her head and was transported to Stroger Hospital, police said.
11-year old Kanari Gentry Bowers and 12-year old Takiya Holmes were both shot in the head, and they're now on life support. Family members told the Chicago Tribune that she was out playing with friends at the time of incident.
But she says she has a message for the person who fired the bullet. She went down immediately. She was shot in the neck and the bullet severed her spinal cord. "We are hopeful that we will see some brain activity". Andrew Holmes, a community activist and Takiya's uncle, offered $1,000 of his own money for information leading to the arrest of the shooter.