Mickens, promoted to the 53-man roster on October 21, made a decisive move upfield, splitting the Bengals' cover unit before outracing them down the left sideline.
Jaguars coach Doug Marrone said rookie receiver Dede Westbrook, who was on injured reserve the first eight weeks of the season following core muscle surgery, could be activated. Green punched Ramsey multiple times while they were both on the ground as players from both teams rushed to break up the fight.
Green caught just 1 pass for 6 yards for 1.1 FanDuel points before being asked to leave the game.
Bortles would connect with Lee on a touchdown pass to take a 10-0 lead and never looked back.
Jaguars kickerJosh Lambo connected on a 56-yard field goal with 23 seconds remaining in the first half.
Beyond the brief melee, the Jaguars put together one of their best offensive halves of the season and led 13-7 at halftime.
The team released a statement shortly before game time saying Fournette was suspended for the game due to a team rule infraction. Without Deshaun Watson for the rest of the year in Houston, Andrew Luck out in Indy and Marcus Mariotta nursing a leg injury in Tennessee, the AFC South is there for the taking. It's one of the four home games remaining and the middle of three straight at the stadium in December.