Ibuprofen Linked To Reduced Fertility In Men
- Author: Santos West Jan 10, 2018,
Jan 10, 2018, 0:28
Now, before you panic, there's no suggestion yet that occasionally relying on an ibuprofen will make your balls shrivel up and die.
"Prescribing providers rarely mention these adverse effects with patients when prescribing these medications", she said, according to CNN, noting that the study was "important" and that the use of ibuprofen could have a far greater negative effect on men who already have low fertility.
Ibuprofen is a non-steroidal anti-inflammatory drug sold without a prescription for short-term treatment of pain, inflammation from injuries, and fever.
Young men taking ibuprofen saw a coordination between luteinizing hormones (LH) - those that produce testosterone - and the level of ibuprofen in their bloodstream.
For now you don't need to worry unless you're a daily user of ibuprofen, and even then, more research will be needed before everyone's shouting about the dangers of painkillers. In addition to producing sperm, testicles secrete testosterone, the primary male hormone. Epidemiological studies have shown that NSAID exposure was associated with reduced testosterone and congenital malformations; another study showed a drop in a testosterone metabolite among men who were taking ibuprofen regularly. Each dose was 600mg, equivalent to three over-the-counter pills. The condition, generally associated with elderly men and linked to reproductive and physical disorders, including infertility, results in the body having higher levels of luteinizing hormone (LH) than testosterone.
Professor Allan Pacey from the University of Sheffield, cautions: "The results suggest that long-term use (several weeks) of ibuprofen can affect the production of the male hormone by the testicles". This amount was used to represent the dose taken by athletes to manage pain.
The finding comes after repeated warnings from other researchers that ibuprofen can raise the risk of heart attacks in the general population and cause medical problems for pregnant women and their babies, including a more than doubling of the risk of miscarriage.
"The safety and efficacy of active ingredients in these products has been well documented and supported by decades of scientific study and real-world use", he added.
To avoid these side-effects, doctors caution against taking Ibuprofen for more longer than ten days in a row, per the FDA's warning.
In the subjects, the condition was temporary, but study leads told the Guardian it could become a permanent problem in cases of long term overuse.