"Grabbing him in the second round was obviously a great treat for us, but character was never a concern", coach Jay Gruden said recently, pointing to injuries and the quality of running backs as reasons for Guice falling in the draft.
Before his injury, Guice was having a strong training camp, taking snaps with the first unit and displaying the same "violent" running style that he was known for.
But now, Guice will spend the 2018 season rehabbing.
In 2012, Adrian Peterson notably returned from the injury and had a career-high 2,097 yards en route to being named the league's MVP. The Redskins were the most injured team last season when accounting for the impact of the players lost, according to Football Outsiders.
The 41-year-old's current deal has two years worth $41 million left that runs through the 2019 campaign, which has left the door open to what the Patriots will do after this upcoming season as he will be in his final year. Payne has made progress and is expected to return soon.
In addition to Thompson, Kelley and Perine will likely be tasked with filling Guice's shoes in the ground game, but unfortunately for Washington, the duo's ceiling doesn't likely come near that of Guice's.
The team also announced that tight end Manasseh Garner will miss the season with an ACL injury sustained in Thursday night's game.