The 17-time Grand Slam champion sent out a statement by dragging the 19-year-old Australian hope over every inch of Rod Laver Arena on his way to a 6-1 6-2 6-4 victory on Friday.
The 2009 Australian Open Champion will now look to pick continuous wins in order to make it to the semi-finals where he is expected to face Roger Federer.
While countrymen Bernard Tomic and Nick Kyrgios continue to capture plenty of headlines for all the wrong reasons de Minaur said he preferred to let his tennis do the talking.
At fleeting moments he even had a glimmer of hope of applying the brakes to the runaway Nadal juggernaut, saving six match points - one after chasing down ball after ball in a lung-bursting 24-shot rally.
"He's a big fighter and super quick. Probably he is the fastest on the tour", Nadal said after the match. "Well, I'm obviously playing some great tennis", he responded. When asked if he wanted to give De Minaur tips on his game, whom Nadal defeated in straight sets, the No. 2 seed answered with a simple, "I will not" that made the crowd burst out in laughter.
"I like how he mixes up his game and also comes to the net".
"It is a feeling that is hard to describe", added the man who is gunning for an 18th Grand Slam crown. At the same stage at Wimbledon a year ago he went down in to an identical 6-1, 6-2, 6-4 scoreline. At this stage of the tournament, Rafael Nadal will play against Tomas Berdych from the Czech Republic.